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Tuesday, 27 January 2015

#Breakingnews: Natural #remedy efficacy in attenuated #Aging & Photo #AgingSpots & #HyperPigmentation Within 3 Months

By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, The Alan Hopkinson Daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com
Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal pharma and Bio science, ISSN 0975-6299.
All right reserved. Reproduction and Translation to other languages of this publication are prohibited without consent of the writer.


 Skin aging is one of the most visible aging processes occurred constantly in our skin. According to the Clinical Centre of Nis, certain plant extracts may have the ability to scavenge free radicals to protect the skin matrix through the inhibition of enzymatic degradation, or to promote collagen synthesis in the skin, and affect skin elasticity and tightness(1).
Dehydroascorbic Acid (DHA) is an oxidized form of vitamin C with Chemical Reaction and Structure as follows


According to Dr. Douglas Q. Kitt, Topical Dehydroascorbic Acid (DHAA) permeates stratum corneum at a rate up to 12 times faster than vitamin C. This supports the concept that lower concentrations of DHAA in topical preparations can enhance skin vitamin C levels with less potential side effects (2).
  
Liver spots or aging spots are condition of brown or black spots appearing on the surface of the skin due to aging and exposure to ultraviolet radiation from the sun. According to skin care guides, high concentration of Vitamin C may improve the skin and lighten the spots(3). Other articles insisted that liver spots may be the result of a deficiency of vitamin C(4). According to the Duke University Medical Center, the application of topical solutions containing vitamins C and E provided protection for human skin against damage caused by ultraviolet radiation(5)6)(7)(8).

According to Dr. Douglas Q. Kitt, Dehydroascorbic Acid (DHAA) permeates stratum corneum at a rate up to 12 times faster than vitamin C. This supports the concept that lower concentrations of DHAA in topical preparations can enhance skin vitamin C levels with less potential side effects (2).

Our previous study(8) indicated that Dehydroascorbic acid (DHA) 4% may effectively attenuate the roughness, scaliness and get rid off most aging spot and photo aging spots on facial skin in our 24 weeks study through it antioxidants, anti inflammation and free radicals scavenging activities.
Re examination facial skin of patients who continuously apply the formula, after 3 months showed a more profound effectiveness.

 Dehydroascorbic acid (DHA) 4% showed effectively in  re smoothing 100% and the getting rid of 100%  aging and photo aging spots in patients with mild expression and to  re smoothing 100% and  getting rid of up to 90%  aging and photo aging spots in patients with serve expression.

In skin pigmentation, resulted of damage most likely caused by UV sunlight, or unhealthy cells due to aging affecting the production of melanin, dehydroascorbic acid (DHA) 4% induced lightening affected areas up 90% through amelioration of the production of melanin, probably through antioxidants and anti inflammatory pathways as in vitamin C in inhibition of reactive nitrogen species (RNS) including nitric oxide (NO)(9).

Kyle J. Norton, the leading researcher said: " the formula is very easy to make, this discovery may benefits everyone who has tried many types of expensive cosmetic product without success". " The contribution of this discovery may some days induced non existence of aging and photo aging spots
in elders and decreased expression on facial hyperpigmentation".

Since the size of study is small, large example size and multi centers studies are necessary to improve this discovery validation and formula effectiveness, before producing the products in large scales to general public.

The equipment and Preparation 1. One bottle of synthetic vitamin C 100x 500mg tablets. You can purchase this in any pharmacy for about $5.00
2. A small bottle carries 100mL of warm tap water or still-water if desire.
3. A roll of bounty or a half hand size sponge.
4. A pair of plastic glove.

How to make Dehydroascorbic acid (DHA) 4% concentration
Day one
Put 8 tablets of synthetic vitamin C into the bottle which carries 100 mL of water[(8x500mg)/100mL=4000mg/100,000mg=4/100=4% concentration of Dehydroascorbic acid (DHA)] on the day before application to make sure all vitamin C tablets are dissolved.

How to remove Liver and Aging spots and re smooth the facial skin 
Liver spot or aging spot is a condition of brown or black spots appeared on the surface of the skin due to aging as the skin is less able to regenerate from sun exposure.
The next day
Put on your glove. Shake the bottle well. Pour some Dehydroascorbic acid (DHA ) onto a piece of fold-twice bounty paper towels. Apply the solution 3 times a days by rubbing against the skin of the effects area with little pressure  for about one minutes. Apply more solution if require.  Dehydroascorbic acid (DHA) 4% concentration should be able to lighten most of Liver and Aging spots and re smooth some of the skin on the effect areas in a few days.

After applying, clean the sponge if used and glove, return  and store the bottle of solution into first aid box in room temperature. Replace the solution every ten days to retain accurate concentration.

What to expect Dehydroascorbic acid (DHA) exhibited its detoxified, antioxidant, lightening and enhanced cell regeneration effects in getting rid of skin damage causes of aging liver and spots and lightening hyperpigmentation due to sun exposure.
  1. In the first few days of application
a. Some of liver or aging spots and hyperpigmentation start to lighten
b. Some of the effected skin area start to smooth out
c. Reduction of visibility of the effect areas
2. Within 3 months
 Dehydroascorbic acid (DHA) 4% showed effectively in  re smoothing 100% in patients with mild and severe expression and getting rid of 90% and 100% aging and photo aging spots respectively in  in patients with  mild and severe expression and lightening 90% of hyperpigmentation.

Precautions 1.  Always testing your topical skin solution, including Dehydroascorbic acid (DHA )  for allergic reaction, by applying a tiny portion onto your wrist for 5 minutes. Do not use the solution if there is allergic reaction.
2. Although there were no adverse effect in our study, please make sure you always wear gloves before applying, as higher concentration of the solution has shown to brownness on the finger nails.
3. The solution has shown to cause yellowness on the surface of some metal (very old) sinks, please make sure your test it to avoid the same messes.
4. Higher concentration of the solution has been used in skin tanning industry,  please make the solution is completely absorbed(about 5- 10 minutes) into your skin before going to the extreme sun.
5. If the solution get into your eyes, use tap water to clear them.
6. Do not attempt to make higher solution and put them on your facial skin, as it has not been tested.

If you have any questions, please email me at kylenorton@live.ca

All articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying

References
(1) Skin ageing: natural weapons and strategies by Binic I1, Lazarevic V, Ljubenovic M, Mojsa J, Sokolovic D.(PubMed)
(2) Topical Dehydroascorbic Acid (Oxidized Vitamin C) Permeates Stratum Corneum More Rapidly Than Ascorbic Acid by Douglas Q Kitt
(3) Liver Spot Removal: Vitamin C Products(Skin care guide)
(4) Lack of vitamin leads to brown spot on hand(livestrong)
(5) A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation by Murray JC1, Burch JA, Streilein RD, Iannacchione MA, Hall RP, Pinnell SR.(PubMed)
(6) UV photoprotection by combination topical antioxidants vitamin C and vitamin E by Lin JY1, Selim MA, Shea CR, Grichnik JM, Omar MM, Monteiro-Riviere NA, Pinnell SR.(PubMed)
(7) Protective effects of topical antioxidants in humans by Dreher F1, Maibach H.(PubMed)
(8) Effectiveness of antioxidants (vitamin C and E) with and without sunscreens as topical photoprotectants by Darr D1, Dunston S, Faust H, Pinnell S.(PubMed)
(9) http://kylejnorton.blogspot.ca/2014/10/anti-skin-aging-in-dehydroascorbic-acid.html
(10) Inhibition of UVA-mediated melanogenesis by ascorbic acid through modulation of antioxidant defense and nitric oxide system. by Panich U1, Tangsupa-a-nan V, Onkoksoong T, Kongtaphan K, Kasetsinsombat K, Akarasereenont P, Wongkajornsilp A.(PubMed)