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Monday, 24 November 2014

Women's Health - Premenstrual syndrome(PMS): The adverse effects of Artificial Sweetener

By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 Premenstrual syndrome is defined as faulty function of the ovaries related to the women's menstrual cycle, effected over 70% to 90% of women in the US and lesser for women in Southeast Asia because of difference in living style and social structure. The syndrome also interferes women's physical and emotional states, and daily activities as a result of hormone fluctuation and occurs one to two weeks before menstruation and then declines when the period starts.

1. Is artificial sweetener safe?
We are made to believe no calories sweetener promoted control weigh(1) and misled in believing that sweetener is better than sugar, Unfortunately, consumption sweetener was associated to weigh gain  in the study of a sample of 22,231 adults(2)
 In fact, it is not true. Sugar helps to provide energy for our body need, over consumption is the problem while sweetener contains aspartame, the substance causes more harm than good to our body including brain(4) and heart(3) and symptoms of pre menstrual syndrome such as depression, mood change(4) and anxiety(5).

2. Serotonin
Artificial sweetener depresses the nervous system(9) in fighting against stress resulting in less levels of serotonin(7) being produced leading to mood swing and depression(4).

3. Amino acids
Amino acids are important for liver in protein metabolism(8). Artificial sweetener contains high levels of aspartic and phenylalanine  over 150 times sweeter than sugar, taking artificial sweetener may cause over dose of such amino acids(10) resulting in increasing the risk of nervous tension leading to memory lose, mood swing, depression and symptoms of PMS(4).

4. Methanol
 When digest, methanol in the sweetener converts to formaldehyde(13) which is toxic to our body resulting in unbalancing the protein metabolism of the brain(12) leading to symptoms of PMS such as mood swing, depression(4) and anxiety(5). if it is over dose.

5. Addictive
The chemical aspartame is so addictive. It is wise to stop taking artificial sweetener slowly or ask your doctor for help. Abruptly stop taking aspartame may cause withdrawal symptoms(13).

6. Obesity and metabolic syndrome
Long term consumption of non-nutritive sweeteners (NNS), particularly aspartame in perigestational period has shown to predispose offspring to develop obesity and metabolic syndrome later in life(6).
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References

(1) Low and no calorie sweeteners (LNCS); myths and realities. Riobó Serván P1, Sierra Poyatos R2, Soldo Rodríguez J3.(PubMed)
(2) Consumption of low-calorie sweeteners among U.S. adults is associated with higher Healthy Eating Index (HEI 2005) scores and more physical activity. Drewnowski A1, Rehm CD2.(PubMed)
(3) Modified High-Density Lipoproteins by Artificial Sweetener, Aspartame, and Saccharin, Showed Loss of Anti-atherosclerotic Activity and Toxicity in Zebrafish. Kim JY1, Park KH, Kim J, Choi I, Cho KH.(PubMed)
(4) Neurobehavioral effects of aspartame consumption. Lindseth GN1, Coolahan SE, Petros TV, Lindseth PD.(PubMed)
(5) Anxiety in mice following acute aspartame and ethanol exposure. LaBuda CJ1, Hale RL.(PubMed)
(6) Exposure to non-nutritive sweeteners during pregnancy and lactation: Impact in programming of metabolic diseases in the progeny later in life. Araújo JR1, Martel F2, Keating E3.(PubMed)
(7) Effects of repeated doses of aspartame on serotonin and its metabolite in various regions of the mouse brain. Sharma RP, Coulombe RA Jr.(PubMed)
(8) Relation between glutamine, branched-chain amino acids, and protein metabolism. Holecek M.(PubMed)
(9) Effects of aspartame metabolites on astrocytes and neurons. Rycerz K1, Jaworska-Adamu JE.(PubMed)
(10) Effect of aspartame and protein, administered in phenylalanine-equivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man. Møller SE.(PubMed)
(11) Aspartame ingestion with and without carbohydrate in phenylketonuric and normal subjects: effect on plasma concentrations of amino acids, glucose, and insulin. Wolf-Novak LC1, Stegink LD, Brummel MC, Persoon TJ, Filer LJ Jr, Bell EF, Ziegler EE, Krause WL.(PubMed)
(12) [Cognitive disorders in workers engaged into formaldehyde and methanol production]. [Article in Russian] [No authors listed](PubMed)
(13) Aspartame Withdrawal Symptoms: List Of Possibilities by Mental Health Daily Mental Health Blog