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Wednesday, 22 October 2014

Endometriosis: The Effects of Blue cohosh (revised edition with references)

 By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.

Blue cohosh (Caulophyllum thalictroides)containing high amount of Saponins, is a species of Caulophyllum and family of Berberidaceae. It is a medium-tall perennial with blue berry-like fruits and bluish-green foliage. It has been used by herbalists in relieving menstrual cramps in traditional medicine.

The effects
1. Reduce menstrual cramps
Blue cohosh is said to contain elements that help in protein and fat metabolism which helps to regulate the production of prostaglandins hormone during the menstrual cycle(1). Over-production of certain hormones of the prostaglandins family causes over-reaction of uterine muscles resulting in abdominal pains.

2. Hormone balancing
It is said that blue cohosh has a property in balancing the estrogen levels(3) by occupying the estrogen receptor sites, thereby it helps to lower levels of estrogen and reduces effects of estrogen dominance that increases the risks of cancer and abnormal cell growth(40.

3. Increase blood flow(5)
Blue cohosh is said to help bring blood to the abdomen and increases the circulation of blood resulting in easing pain caused by blood stagnation during menstrual period.

4. Nervous system(2)
Blue cohosh is an antispamsmodic that helps to ease tension of nervous system(3)(4) resulting in reducing symptoms of endometriosis during menstrual cycle.

5. Phytoestrogen(3)(4)
Blue cohosh contains phytoestrogen which helps to reduce the levels of bad estrogen that causes menstrual cramps.
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References
(1) Alkaloids and saponins from blue cohosh by Ali Z1, Khan IA.(PubMed)
(2) Saponins in the genus Panax L. (Araliaceae): a systematic review of their chemical diversity.by Yang WZ1, Hu Y2, Wu WY1, Ye M3, Guo DA4.(PubMed)
(3) Anti-inflammatory and neuroprotective effect of a phytoestrogen compound on rat microgliaby Marotta F1, Mao GS, Liu T, Chui DH, Lorenzetti A, Xiao Y, Marandola P.(PubMed)
(4) Isoflavones: Chemistry, Analysis, Functions and Effects on Health and Cancer.by Ko KP.(PubMed)
(5) Dietary intake of phytoestrogen is associated with increased circulating endothelial progenitor cells in patients with cardiovascular disease by Chan YH1, Lam TH, Lau KK, Yiu KH, Siu CW, Li SW, Chan HT, Tam S, Lau CP, Tse HF.(PubMed)