Garlic has been used in traditional Chinese and herbal medicine over
thousands of year as antibacterial, antiviral, and antifungal agent and
in treating other conditions such as parasites, respiratory problems,
poor digestion, low energy, etc. In many studies, researchers found
that Allyl sulfides, a phytochemical in garlic has been demonstrated
effectively in treating certain diseases.
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B. The effects of Phytochemicals Allyl sulfides in Women's health
1. Bone health
Allyl
sulfides can be beneficial in preventing bone loss for women with
osteoporosis and in the stage of perimenopause, menopause and
postmenopause.In a study of "Prevention
of bone loss by oil extract of garlic (Allium sativum Linn.) in an
ovariectomized rat model of osteoporosis." by Mukherjee M, Das AS, Mitra
S, Mitra C. (Department
of Physiology, Presidency College, Kolkata-700073, India.) posted in
US National Library of Medicine National Institutes of Health,
researchers found that Garlic oil extract supplementation, apart from
its unique influence in lowering blood cholesterol, could also
prevent ovariectomy-induced rise in all the above-mentioned marker
changes. The results of this study emphasize that oil extract of
garlic possibly has a positive role in suppressing
ovariectomy-induced bone resorption.
2. Breast cancer
Allyl sulfides is one of many phytochemicials shown to suppress the proliferation of various tumor cells, according to the study of "Antiproliferative
effect of natural tetrasulfides in human breast cancer cells is
mediated through the inhibition of the cell division cycle 25
phosphatases" by Viry E, Anwar A, Kirsch G, Jacob C, Diederich M, Bagrel
D., posted PubMed,
researchers wrote that on the inhibitory activity of tetrasulfides
occurring naturally in garlic and onion towards the human Cdc25
phosphatases. Diallyl- and dipropyltetrasulfides have emerged as
interesting irreversible inhibitors of the Cdc25 isoforms A and C in
vitro. Furthermore, growth of both sensitive (MCF-7) and resistant
(Vcr-R) human breast carcinoma cells was significantly decreased by
these tetrasulfides. The observed antiproliferative effect appeared to
be associated with a G2-M cell cycle arrest.
3. Cervical cancer
According
to the study of "Reversal of hypermethylation and reactivation of the
RARβ2 gene by natural compounds in cervical cancer cell lines" by Jha
AK, Nikbakht M, Parashar G, Shrivastava A, Capalash N, Kaur J., posted
in PubMed, researchers found that allyl
sulphide treatment (20 μM) did not cause the reversal of
hypermethylation until 72 h of treatment in the SiHa cell line. This is
the first report to show the reversal of hypermethylation of the RARβ2
gene by genistein and curcumin in cervical cancer cell lines.
Furthermore, these compounds acted as doublepronged agents as they
caused apoptosis in the treated cervical cancer cell lines in addition
to reversal of promoter hypermethylation.
4. Vaginal infection
Allyl
sulfides is considered by herbalist as a herb used to treat certain
infections, including candidiasis cause of vaginal infection, according
to the article of "Garlic: Herbal Remedies" by Jennifer Brett, N.D.,
posted in Discovery fit and health, the author wrote that Garlic is used
to treat many types of infections: Use capsules internally for
recurrent vaginal yeast infections, use a garlic infusion topically as a
soak for athlete's foot, or add garlic to an oil to treat middle ear
infections.
5. Etc.
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Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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