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Saturday, 7 December 2013

Menstrual Migraines - The Symptoms and Causes

I. Menstrual Migraines is a hormone related headaches happened in the before, during or immediately after the period, or during ovulation as a result of the levels of estrogen and progesterone fluctuations in the menstrual cycle.

II. Symptoms
1. Headaches
2. Sensitivity to noise, light, smell or various combinations can worsen the headache
3.  Mood swing and fatigue
4.  Joints and muscles pain
5. Vomiting 
6. Scotomas
7. Nausea, backache, breast tenderness, and cramps.
8. Etc.

III. Causes
Menstrual migraines share many clinical characteristics of other types of migraines, but their occurrence is also give a woman a prediction of the coming of regular menstrual cycles
1. Hormone fluctuation
The drop of both hormones estrogen and progesterone in the final phase of the menstrual period must be in the harnomization state to prevent any disruption of the start of the first phase of the next menstrual cycle. In some women, because of the fluctuation of the hormones in the last stage, leading to menstrual headaches. Other researchers suggested that gonadal hormone fluctuation may influence both types of migraine(1)

2. Control pills
In the same report above, researchers also said women in the study who are taking oral contraceptive pill are also experience the aura symptom for the first time in the early cycles(1)

3.  Menopausal hormonal replacement therapy
Women who are in post-menopause stage, taken the hormonal replacement therapy to relieve the menopause symptoms are at higher risk of the development of menstrual migraine.

4. Periodic discontinuation of oral sex hormone preparations
Period discontinuation of oral sex hormone can cause fluctuation of hormones in the menstrual cycle of which may increase the risk of menstrual migraine.

5. OCs using
In a double-blind, controlled, randomized, four-arm, bicentric clinical study, the effect of four oral contraceptives (OCs) on various hormone parameters and serum-binding globulins, conducted by , J. W. Geothe University, there was a significant increase in the levels of serum-binding globulins during treatment, which differed according to the composition of the OCs used, of which may enhance the risk of menstrual migraine(3)

6. First trimester of pregnancy
Migraine may worsen during the first trimester of pregnancy and, although many women become headache-free during the last two trimesters, 25p. 100 have no change in their migraine (Silberstein, 1997). MM typically improves with pregnancy, perhaps due to sustained high estrogen levels (Silberstein, 1997)(2)

7. Serotonergic tone
The estrogen withdrawal that occurs just prior to the onset of menses may lead to the loss of serotonergic tonewhich is thought to be the trigger for headaches that arise at this time of the menstrual cycle.(4)

8.  Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/7641250
(2) http://www.ncbi.nlm.nih.gov/pubmed/11139745
(3) http://www.ncbi.nlm.nih.gov/pubmed/12521654 
(4) http://www.ncbi.nlm.nih.gov/pubmed/17044842