In the review of studies of participants who fulfilled the following
criteria: 1) they were randomised controlled clinical trials of low-fat
diets versus other weight-reducing diets, 2) the primary purpose of the study was weight loss,
3) participants were followed for at least six months, 4) the study
participants were adults (18 years or older) who were overweight or
obese (BMI >25 kg/m2) at baseline. Studies including pregnant women
or patients with serious medical conditions were excluded. Two people
independently applied the inclusion criteria to the studies identified.
Disagreement was resolved by discussion or by intervention of a third
party, conducted by University of Teesside (1) focused primarily on
participants who were overweight or clinically obese and were dieting
for the purpose of weight reduction. Since we were particularly interested in the ability of participants to sustain weight loss
over a longer period of time, we focused on studies of 'free living'
men and women who were given dietary advice rather than provision of
food or money to purchase food. The review suggests that fat-restricted
diets are no better than calorie restricted diets in achieving long
term weight loss in overweight or obese people. Overall, participants lost slightly more weight on the control diets but this was not significantly different from the weight loss achieved through dietary fat restriction and was so small as to be clinically insignificant.
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(1) "WITHDRAWN: Advice on low-fat diets for obesity" by Summerbell CD, Cameron C, Glasziou PP., posted in PubMed(1)
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