Tuesday 3 December 2013

Gallstone Preventions - The Diet

A gallstone formed within the gallbladder as a result of changes in bile acid (BA) metabolism and gallbladder function are critical factors in the pathogenesis of gallstones. Gallstones can cause blockage the flow of bile through the bile ducts that can lead to inflammatory causes of  acute cholecystitis. Gallstones are most common among older adults, women, overweight people, etc.
Prevention
1. Vegetable
Vegetable protein may reduce the risk of cholelithiasis(19)

2. A low-fat, low-protein, high-carbohydrate or lowering of glycaemic index and the caloric reduction diet may reduce the risk of formation of gallstone formation(21)

3. Reduce intake of bad fat(23)
In the study of found  that  the type of dietary fat habitually consumed can influence bile composition in humans. In gallbladder, this influence was noted in the presence of more concentrated bile in the olive oil group. However, this was not translated into a modification of cholesterol saturation, which is likely due to the fact that cholesterol gallstones were present by the time the dietary intervention started(22).

4. Nuts
Nuts (tree nuts and peanuts) are nutrient dense foods with complex matrices rich in unsaturated fatty and other bioactive compounds: high-quality vegetable protein, fiber, minerals, tocopherols, phytosterols, and phenolic compounds According to the study by Dr, Ros E nuts are likely to beneficially impact health outcomes. Epidemiologic studies have associated nut consumption with a reduced incidence of coronary heart disease and gallstones in both genders and diabetes in women(20).

5. Wheat bran
There is a study of 10 patients with probable cholesterol gallstones took bran supplements for 4-6 weeks, their gallbladder bile aspirated from the duodenum became less saturated with cholesterol(24).

6. Others
Some researchers suggested that intake of high energy, simple sugar and saturated fat favors gallstone formation. Fiber and moderate consumption of alcohol reduce the risk(25).
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Sources
(19) http://www.ncbi.nlm.nih.gov/pubmed/1503808
(20) http://www.ncbi.nlm.nih.gov/pubmed/22254047
(21) http://www.ncbi.nlm.nih.gov/pubmed/14619611
(22) http://www.ncbi.nlm.nih.gov/pubmed/15797676
(23) http://www.ncbi.nlm.nih.gov/pubmed/1398503
(24) http://www.ncbi.nlm.nih.gov/pubmed/941893
(25) http://www.ncbi.nlm.nih.gov/pubmed/15190042 

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