Tuesday 3 December 2013

Duodenitis Prevention - The Antioxidants

Duodenitis is defined as a condition of inflammation in the lining of the duodenum, the first section of the small intestine. 
Antioxidant to prevent Duodenitis
The aim of antioxidants is to enhance the inmmue function ain fighting against invasion as result of bacterial, viral and parasitic causes of inflammation.
1. Quercetin
Since it contains high amount of antioxidants, onion enhances the immune system in fighting against the forming of free radicals and foreign invasion, thus eeducing the symptoms of inflammatory conditions such as arthritis and gout and infection caused by bacteria, including E.coli and salmonella,etc., according to the study of Antibacterial and antioxidant activities of quercetin oxidation products from yellow onion (Allium cepa) skin.(30).

2. Bromelain
Today Pineapple is widely cultivated for commercial and its rich of vitamins and mineral and digesting enzyme bromelin which seems to help digestion at the end of a high protein meal. It is second only to banana as America's most favourite tropical fruit. In the classification of bromelain is a mixture of proteinases derived from pineapple stem and its effect in gastrointestinal tract, found that bromelain enzymes can remain intact and proteolytically active within the murine gastrointestinal tract. They provide further support for the hypothesis that oral bromelain may potentially modify inflammation within the gastrointestinal tract via local proteolytic activity within the colonic microenvironment, according to "Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice" by Hale LP.(31). Also Bromelain also increases the immune function in fighting the invasion of foreign substances such as bacteria and virus, thus decreasing the risk of inflammation and infection according to the study of "Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro" by Secor ER Jr, Singh A, Guernsey LA, McNamara JT, Zhan L, Maulik N, Thrall RS., posted in PubMed(32).

3. Polyphenols
Polyphenols, one of more powerful form of antioxidant not only helps to improve the immune system fighting against the forming of free radicals and guarding our body from foreign invasion, such as virus and bacteria, thus reducing the risk of inflammation and lessening the risk of oxidation of low-density lipoprotein (LDL) cause coronary heart disease, according to the study of "Plant polyphenols as dietary antioxidants in human health and disease" by Kanti Bhooshan Pandey and Syed Ibrahim Rizvi, posted in PubMed Central(33).

4. Catechins
Catechins are a category of polyphenols contained epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin gallate (EGCG) and 25-100 times more potent than vitamins C and E that help to protect the body from oxidative damage by enhancing the immune function in fighting against forming of free radicals cause of cancer, according to the study of "Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer" by Liang G, Tang A, Lin X, Li L, Zhang S, Huang Z, Tang H, Li QQ.(34).

5. LycopeneLycopene, one of the powerful antioxidant in tomatoes, not only helps the immune system in neutralizing the forming of free radicals in the body and according to Harvard investigation as it found that men who ate more than 10 servings tomato-based foods daily (like cooked tomatoes and tomato sauce,) had a 35 percent lower risk of developing prostate cancer than those who ate the least amount of these foods. The benefits of lycopene was more pronounced with advanced stages of prostate cancer. Also according to the study of "Chemoprevention of prostate cancer with lycopene in the TRAMP model" by Konijeti R, Henning S, Moro A, Sheikh A, Elashoff D, Shapiro A, Ku M, Said JW, Heber D, Cohen P, Aronson WJ.(35),.

6. Etc. 

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Sources

(30) http://www.ncbi.nlm.nih.gov/pubmed/19127724
(31) http://www.ncbi.nlm.nih.gov/pubmed/14996417
(32) http://www.ncbi.nlm.nih.gov/pubmed/19162239
(33) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835915/
(34) http://www.ncbi.nlm.nih.gov/pubmed/20514403
(35) http://www.ncbi.nlm.nih.gov/pubmed/20687227
 

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