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Sunday, 1 December 2013

Anorexia nervosa - The Antioxidants

Anorexia nervosa
Anorexia nervosa is a type of eating disorder usually develop in the teen years and effect over 90% of female, because of excessive food restriction and irrational fear to become fat due the wrongly influenced media as attractiveness is equated to thinness.
Prventions
Antioxidants to prevent anorexia nervosa
An antioxidant is a chemical that  protect cells against damage caused by free radicals and chain reaction of free radicals by inhibiting the oxidation of other molecules
 1. In the study of the antioxidant status in female adolescents (N = 82) with anorexia nervosa, by the measurement of erythrocyte tocopherol concentration, and the determination of activities of the main antioxidant enzymes: superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase.
showed that tocopherol was significantly decreased in the anorexic patients compared to reference values (p < .02). In 21% of patients, tocopherol levels were below the reference interval. Superoxide dismutase activity was significantly decreased (p < .0001), while catalase activity was increased (p < .0001). The activity of the glutathione system enzymes did not show significant differences between patients and controls.The deficient concentration of erythrocyte tocopherol together with the altered antioxidant enzyme activities suggest a certain degree of oxidative damage in anorexia nervosa owing to both factors deficient micronutrient intake and oxidative stress(49).

2. Antioxidant vitamins in Anorexia Nervosa by V. MATZKIN¹, C. GEISSLER¹ and M. BELLO, indicated that antioxidant vitamins (tocopherol, retinol and carotene) protect against lipid peroxidation caused by free radicals and active oxygen species. Patients with Anorexia Nervosa (AN) are at a greater risk of oxidative damage due to undernutrition and stress (Moyano, et. al., 1999). There is contradictory evidence concerning concentrations of tocopherol (Mira et. al. 1987, Phillip et. al., 1998 and Moyano et. al., 1999), retinol (Robboy et. al., 1974, Lagan and Farrell, 1985 and Vaisman, et. al., 1992) and carotene (Van Binsbergen et. al., 1988, Rock et. al., 1996) in AN(50).

3. Etc.
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Sources
(49) http://www.ncbi.nlm.nih.gov/pubmed/9924658
(50) http://www.fac.org.ar/fec/foros/cardtran/gral/antioxidant.htm