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Saturday, 30 November 2013

Shingles - The Diet

Shingles also known as herpes zoster or zona is defined as a viral disease with condition of a painful, blistering skin rash on one side of the body of  that can continue to be painful even after the rash have long disappeared(1), as a result of varicella-zoster viral causes of a nerve and skin inflammation.
Diet against shingles
The aims of the diet against shingle is to enhace the immune system by taking fruits and vegatables which contains high amount of antioxidant to fight off the viral causes of infections
1. Wolfberry is the common name for the fruit of two very closely related species, the genus of Lycium, belong to family Solanaceae, native to native to southeastern Europe and Asia.
a.  Anticancer and immunomodulatory effects
In the classification of the anticancer effects of traditional Chinese medicine (TCM) used in cancer therapies found that major active ingredients, L. barbarum polysaccharides (LBP), scopoletin and 2-O-β-D: -glucopyranosyl-L: -ascorbic acid (AA-2βG), are found to have apoptotic and antiproliferative effects on cancer cell lines. Moreover, LBP also contributes to body's immunomodulatory effects and enhances effects of other cancer therapies. It is not known whether there are any undesirable effects, according to "A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit" by Tang WM, Chan E, Kwok CY, Lee YK, Wu JH, Wan CW, Chan RY, Yu PH, Chan SW.(20)

b. Hypochlolesterolemic and antioxidative effects
In the researches of the hypocholesterolemic effect and potential of tyramine derivatives from Lycii Cortex Radicis (LCR), the root bark of lycium (Lycium chenese Miller) in reducing lipid peroxidation found that The level of liver cholesterol was significantly lower in LCR1 and LCR2 groups than HF-control. Serum levels of TBARS were significantly lower only in LCR2 group when compared with HF-control group. From the observed results, we concluded that LCR can be utilized as a hypocholesterolemic ingredient in combination with ginger, especially for functional foods, according to "Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller" by Cho SH, Park EJ, Kim EO, Choi SW.(21)

2. Oranges
Orange is a species of Citrus Sinensis, belong to the family Rutaceae and native to the Southeast Asia. Orange is round citrus fruits with finely-textured skins, orange in color and one of most popular fruits in the world.
a. Bioavailability and antioxidant effects
In the reserach of Bioavailability and antioxidant effects of orange juice (OJ) into habitual diet found that after the 3 week intervention, plasma concentrations of vitamins A and E did not change. 8-Hydroxydeoxyguanosine in white blood cells declined by 16% (p = 0.38; n = 11), and in individuals with high baseline concentrations by 29% (p = 0.36; n = 7), respectively. Low-density lipoprotein (LDL)-/high-density lipoprotein (HDL)-cholesterol ratios decreased but cholesterol (HDL, LDL, total) and thiobarbituric acid reactive substance plasma concentrations did not change significantly, according to "Bioavailability and antioxidant effects of orange juice components in humans?" by Franke AA, Cooney RV, Henning SM, Custer LJ.(22)

b.  Vitamin C
a. Capillaries
Since it contains high amount of vitamin C, it reduces the risk of breaking off of the small vessels, thus preventing the risk of infection, inflammation, according to the study of "High-dose vitamin C treatment reduces capillary leakage after burn plasma transfer in rats" by Kremer T, Harenberg P, Hernekamp F, Riedel K, Gebhardt MM, Germann G, Heitmann C, Walther A.(23)

b. Immune system
Vitamin C is considered as on of most powerful free radical scavenger, it helps to enhane the immune system fighting against forming of free radical cause of irregular cells growth due to mutation of cells' DNA, including tumors and cancers, according to the study of "Vitamin C and cancer: what can we conclude--1,609 patients and 33 years later?" by Cabanillas F.(24)

2. Pomegranates is a fruit-bearing small tree, genus Punica, belonging to family Lythraceae, native to Iran but has been cultivated in Asian since ancient time.
a.  Antiproliferative, apoptotic and antioxidant activities
In the assessment of polyphenols including punicalagin, the major fruit ellagitannin, and ellagic acid (EA) of Pomegranate (Punica granatum L.) fruits juice (PJ) and its antioxidant and anti-atherosclerotic activities found that Pomegranate juice showed greatest antiproliferative activity against all cell lines by inhibiting proliferation from 30% to 100%. At 100 microg/ml, PJ, EA, punicalagin and TPT induced apoptosis in HT-29 colon cells. However, in the HCT116 colon cells, EA, punicalagin and TPT but not PJ induced apoptosis. The trend in antioxidant activity was PJ>TPT>punicalagin>EA. The superior bioactivity of PJ compared to its purified polyphenols illustrated the multifactorial effects and chemical synergy of the action of multiple compounds compared to single purified active ingredients, according to "In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice" by Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D.(25)

b. CatechinsCatechin, a polyphenol found abundantly in Pomegranates has exerted its antioxidant effect in reducing the risk of forming of free radicals, according to "Catechins and procyanidins in berries of vaccinium species and their antioxidant activity" by Määttä-Riihinen KR, Kähkönen MP, Törrönen AR, Heinonen IM.(26)

5.  Blueberry is a flower plant, belong to the family Eriaceae and native to Northern America. It can grows from 10 cm to 4 meters tall.
In the investigation of Blueberry and blackberry wines commercially available in Illinois and theirs potential health benefits, found that fruit wines made from blueberries and blackberries may have potential health applications and therefore could contribute to the economy of the wine industry. Practical Application: The majority of wines are produced from grapes, but wine can also be produced from other fruits including blueberries and blackberries, which contain phenolic compounds that may contribute to human health, according to "Comparison of Chemical Composition and Antioxidant Capacity of Commercially Available Blueberry and Blackberry Wines in Illinois" by Johnson MH, Gonzalez de Mejia E.(27)

6. Coriander is an annual herb, genus Coriandrum in the family Apiaceae, native to southern Europe and North Africa to southwestern Asia. All parts of the plant are edible, but the fresh leaves and the dried seeds are the parts most commonly used in cooking.
a. Anti-anxiety activity
In the evaluation of anti-anxiety activity of hydroalcoholic extract of Coriandrum sativum (Linn.) found that extract of C. sativum at 100 and 200 mg/kg dose produced anti-anxiety effects almost similar to diazepam, and at 50 mg/kg dose did not produce anti-anxiety activity on any of the paradigm used, according to "Anti-anxiety activity of Coriandrum sativum assessed using different experimental anxiety models" by Mahendra P, Bisht S.(28)

b. Antioxidant and hepatoprotective effect
In the investigation of essential oils of Coriandrum sativum L. and Carum carvi L. fruits and their antioxidant activity and hepatoprotective effect against carbon tetrachloride (CCl(4)) damage found that coriander essential oil exhibited prooxidant activity, according to "Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae)" by Samojlik I, Lakić N, Mimica-Dukić N, Daković-Svajcer K, Bozin B.(29)

7. Etc

There is no specific fruits or vegetables for preventing shingle, please consult the world most healthy foods for more enhanced immune system foods(30).

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16936604
(20) http://www.ncbi.nlm.nih.gov/pubmed/22189914
(21) http://www.ncbi.nlm.nih.gov/pubmed/22125678 
(22) http://www.ncbi.nlm.nih.gov/pubmed/15969493 
(23) http://www.ncbi.nlm.nih.gov/pubmed/20354446
(24) http://www.ncbi.nlm.nih.gov/pubmed/20799507 
(25) http://www.ncbi.nlm.nih.gov/pubmed/15936648 
(26) http://www.ncbi.nlm.nih.gov/pubmed/16248542 
(27) http://www.ncbi.nlm.nih.gov/pubmed/22182198 
(28) http://www.ncbi.nlm.nih.gov/pubmed/22022003
(29) http://www.ncbi.nlm.nih.gov/pubmed/20608729 
(30) http://medicaladvisorjournals.blogspot.ca/2011/12/popular-super-foods-health-benefits-and.html