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Saturday, 30 November 2013

Shingles - The Complications

I. Shingles also known as herpes zoster or zona is defined as a viral disease with condition of a painful, blistering skin rash on one side of the body of  that can continue to be painful even after the rash have long disappeared(1), as a result of varicella-zoster viral causes of a nerve and skin inflammation.
Complications
1. Anterior uveitis
In the study to investigate the relationship between herpes zoster (HZ) and the subsequent risk of anterior uveitis during the year following an HZ diagnosis, Dr. Wang TJ, and the team at the Taipei Medical University suggested that The risk of anterior uveitis increased in the year following a diagnosis of HZ. and suggest that patient eye condition be evaluated following diagnosis with HZ(8).

2. Stroke
In the study to investigate the risk of stroke development following a diagnosis of herpes zoster ophthalmicus (HZO), Dr. Lin HC and the team at the Taipei Medical University Hospital herpes zoster ophthalmicus may represent a marker of increased risk of stroke development during the 1-year follow-up period(9).

3. Occipital neuralgia
Paroxysmal shooting or stabbing pain in the dermatomes of the nervus occipitalis major or nervus occipitalis minor is defined as occipital neuralgia. The initial cause of the neuralgia appears to be from inflammation, damage or irritation of these nerves. In this article, we present a patient with occipital neuralgia followed by thoracic herpes lesion(10).

4. Bullous Variant of Sweet's Syndrome 
Dr. Yuichiro Endo, and the researcher team at the Department of Dermatology, Kyoto University, Kyoto, reported a case of a 75-year-old male presented to our department with haemorrhagic and erosive plaques on the left side of the face and neck. After discussion they said that our case was unique in that herpes zoster virus infection seemed to trigger the development of bullous variant of SS. We think the preceding blisters were not caused by SS, but rather by the herpes zoster virus infection because the initial lesion subsided when SS progressed(11).

5. Etc.
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Sources
(2) http://www.aafp.org/afp/2008/0501/p1307.html
(8) http://www.ncbi.nlm.nih.gov/pubmed/22491915 
(9) http://www.ncbi.nlm.nih.gov/pubmed/20200348
(10) http://www.ncbi.nlm.nih.gov/pubmed/22290683
(11) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250670/?tool=pubmed