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Saturday, 30 November 2013

Shingles Treatments In the conventional medicine perspective

Shingles also known as herpes zoster or zona is defined as a viral disease with condition of a painful, blistering skin rash on one side of the body of  that can continue to be painful even after the rash have long disappeared(1), as a result of varicella-zoster viral causes of a nerve and skin inflammation.
Treatments
A. In the conventional medicine perspective
1. Topical cream
Some researchers suggest that the lidocaine plaster could be at least as effective as systemic pregabalin in the treatment of postherpetic neuralgia and painful diabetic polyneuropathy. Open-label studies indicate efficacy in the treatment of other localized neuropathic pain conditions, such as painful idiopathic sensory polyneuropathy, complex regional pain syndrome, carpal tunnel syndrome sequelae, postsurgical and posttraumatic pain. Quality of life markedly improved in a variety of neuropathic pain conditions and long-term treatment provided sustained relief in patients with neuropathic pain who are responsive to lidocaine plaster. The lidocaine plaster is usually well tolerated. The risk of systemic adverse events and pharmacokinetic interactions with concomitant medication is minimal owing to low systemic exposure(d)

2. Other medication
Dr. Kofoed K. and the team of researchers at the Dermato-venerologisk Afdeling D41, Bispebjerg Hospital, showed that Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show that early recognition and treatment can reduce acute symptoms, that antiviral therapy and corticosteroids shorten the acute illness period, that opioids and anticonvulsants have effect on acute HZ pain and, finally, that tricyclic antidepressants, opioids and anticonvulsants all have proven efficiency in PHN therapy.(e)

3. Etc.
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Sources
(a) "Effect of protein-xanthophylls (PX) concentrate of alfalfa supplementation on physico-chemical properties of turkey breast and thigh muscles during ageing" by Karwowska M, Stadnik J, Dolatowski ZJ, Grela ER., posted in PubMed
hyperlipoproteinemia", posted in PubMed
(b) " The ethyl acetate extract of alfalfa sprout ameliorates disease severity of autoimmune-prone MRL-lpr/lpr mice" by Hong YH, Huang CJ, Wang SC, Lin BF., posted in PubMed
(c) "Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide-induced inflam

(d) http://www.ncbi.nlm.nih.gov/pubmed/22551228
(e) http://www.ncbi.nlm.nih.gov/pubmed/21219842
(1) http://www.ncbi.nlm.nih.gov/pubmed/16936604