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Wednesday, 27 November 2013

Restrictive lung diseases (Respiratory Disease) – Treatments In traditional Chinese medicine perspective

Respiratory Disease is defined as medical conditions, affected the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and  muscles breathing , etc,.
Restrictive lung diseases or restrictive ventilatory defects
Restrictive lung disease is a condition marked most obviously by a reduction in total lung capacity. A restrictive ventilatory defect may be caused by a pulmonary deficit, such as pulmonary fibrosis (abnormally stiff, non-compliant lungs), or by non-pulmonary deficits, including respiratory muscle weakness, paralysis, and deformity or rigidity of the chest wall(1).
F. Treatments
F.3. In traditional Chinese medicine perspective
Pulmonary fibrosis (PF) is a restrictive lung disease that may occur idiopathically or as a complication of many diseases. In the study to test a new Chinese medicine formula DSQRL for the treatment of experimental PF in comparison with prednisone, conducted by Hong Kong Baptist University, Hong Kong, showed that at the end of 30 days treatment, the DSQRL treatment achieved a better outcome (p<0.05) than prednisone in terms of histological examination, bronchoalveolar lavage fluid analysis, hydroxyproline assay and complications(36). In other study by the same university to compare the Chinese medicine formula DSQRL from glucocorticoids, indicated that at the end of 60 days treatment, the DSQRL treatment achieved a significantly better outcome than prednisolone in terms of general behavior, histological examination, hydroxyproline content of the lung and inflammatory cell counts in bronchoalveolar lavage fluid(37) 
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Sources
(1) http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(37) http://www.ncbi.nlm.nih.gov/pubmed/18191351