Pulmonary arterial hypertension
Pulmonary arterial hypertension is a subgroup of a specific subgroup of pulmonary hypertension (PH) defined as a condition of slowly progressive disorder as a result of abnormally high blood pressure in the blood vessel, including pulmonary artery, pulmonary vein, or pulmonary capillaries, that carries blood from the heart to the lungs due to narrowing in diameter of most of the very small arteries throughout the lungs of that increased resistance to blood flow, leading to right heart failure and death. Because the phrase of pulmonary arterial hypertension is long and pulmonary hypertension is a bit shorter the phrase, pulmonary hypertension is often used in place of pulmonary arterial hypertension(a). According to statistic, approximately over 1,000 new cases of pulmonary arterial hypertension are diagnosed each year, in the United States alone.
C. In traditional Chinese perspective
1. Chinese herbs Naofeikang
In the sturdy to evaluate the preventive and therapeutic effect of Chinese herbs Naofeikang on hypoxic pulmonary artery hypertension of elastase-induced emphysema hamsters and its mechanism, by the Department of Pathology, FUWAI Hospital, CAMS, PUMC, indicated that Chinese herbs Naofeikang could lower pulmonary hypertension, preserve vessel endothelial cells and lessen the inflammatory reaction in pulmonary tissue. Thereby, it could hinder the further development of emphysema and inhibit the remodeling of pulmonary small artery(40).
2.”Qi-Xue” injection (Panax ginseng, Astragalus monogholicus, Angelica sinensis)
In the study by the Institute of Basic Medical Sciences of the effects of “Qi-Xue” injection (Panax ginseng, Astragalus monogholicus, Angelica sinensis), verapamil (Vp, calcium antagonist) and their combination on pulmonary arterial pressure (PAP) and heart function in rats exposed to chronic hypoxia, indicated that both “Qi-Xue” injection and Vp minimized the increase in PAP due to hypoxia, with the former being more effective than the latter. “Qi-Xue” injection also attenuated IC-R decrease and kept it in the normal range. No appreciable differences were observed between the effect of “Qi-Xue” and its combination with Vp. It is suggested that “Qi-Xue” injection might prevent the development of severe hypoxic pulmonary hypertension by improving heart function(41).
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