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Sunday, 3 November 2013

Popular #Herbs - Muira Puama (Ptychopetalum)


Muira Puama is a flowering plants in the genus of Ptychopetalum in thefamily Olacaceae, native to the Amazon rainforest.The herb has been used in traditional medicine to enhance sexual desire, erectile function and to treat dysentery, rheumatism nervous tension, depression, etc.

Health benefits
1. Sex drive
In the assessment of he efficacy of a unique herbal formulation of Muira puama and Ginkgo biloba (Herbal vX) in the treatment of sexual dysfunction in healthy women, found thatStatistically significant improvements occurred in frequency of sexual desires, sexual intercourse, and sexual fantasies, as well as in satisfaction with sex life, intensity of sexual desires, excitement of fantasies, ability to reach orgasm, and intensity of orgasm. Reported compliance and tolerability were good. These initial findings support the strong anecdotal evidence for the benefits of Herbal vX on the female sex drive, according to "Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women" by Waynberg J, Brewer S.(1)

2. Neurodegenerative conditions
In the identification of a standardized ethanol extract from Ptychopetalum olacoides (POEE), a medicinal plant favored by the elderly in Amazon communities and its inhibition in brain areas relevant to cognition found that this study provides definitive proof of meaningful anticholinesterase activity compatible with the observed promnesic and anti-amnesic effects of POEE in mice, reaffirming the potential of this extract for treating neurodegenerative conditions where a hypofunctioning cholinergic neurotransmission is prominent, according to "Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Marapuama)" by Figueiró M, Ilha J, Pochmann D, Porciúncula LO, Xavier LL, Achaval M, Nunes DS, Elisabetsky E.(2)

3. Anti-stress effects
In the investigation of Marapuama (Ptychopetalum olacoides Bentham, PO and its anti-stress properties found that Ptychopetalum olacoides (Marapuama) might possess adaptogen-like properties, according to "Anti-stress effects of the "tonic"Ptychopetalum olacoides (Marapuama) in mice" by Piato AL, Detanico BC, Linck VM, Herrmann AP, Nunes DS, Elisabetsky E.(3)

4. Antioxidant activities
In the identification of of PO ethanol extract (POEE) free-radical scavenging properties in vitro, found that POEE administration reduced free-radical production in the hypothalamus, lead to significant decrease in lipid peroxidation in the cerebral cortex, striatum and hypothalamus, as well as in the carbonyl content in cerebellum and striatum. In terms of antioxidant enzymes, catalase activity was increased in the cortex, striatum, cerebellum and hippocampus, while glutathione peroxidase activity was increased in the hippocampus and concluded that POEE contains compounds able to improve the cellular antioxidant network efficacy in the brain, ultimately reducing the damage caused by oxidative stress, according to "Antioxidant activities of Ptychopetalum olacoides ("muirapuama") in mice brain" by Siqueira IR, Fochesatto C, Torres IL, da Silva AL, Nunes DS, Elisabetsky E, Netto CA.(4)

5. Anxiogenic properties
In the assessment of Alcohol infusions of roots of Ptychopetalum olacoides Benth. (PO), known as Marapuama or Muirapuama, used in the Brazilian Amazon as a 'nerve tonic' found that
found that P. olacoides ethanol extract (30, 100 and 300 mg/kg) decreased exploratory behaviour in the hole-board test, without interfering with locomotion or motor coordination (rota-rod test), according to "Anxiogenic properties of Ptychopetalum olacoides Benth. (Marapuama)" by da Silva AL, Bardini S, Nunes DS, Elisabetsky E.(5)

6. Antidepression effect
In the investigation of standardized PO ethanol extract (POEE) on the forced swimming (FST) and tail suspension tests (TST) and theirs antidepression effect found that Consistent with traditional use, the results indicate that POEE possesses antidepressant-like effects, possibly mediated by beta-adrenergic and D(1) dopamine receptors, according to "Antidepressant profile of Ptychopetalum olacoides Bentham (Marapuama) in mice" by Piato AL, Rizon LP, Martins BS, Nunes DS, Elisabetsky E.(6)

7. Etc.

Side effects
1. Overdoses may cause nervous tension, including insomnia and restlessness
2. Do not use the herb in Children, or if you are pregnant or breast feeding without approval from the related field specialist
3. Do not use the herb combination with other sexual stimulants.
4. Etc.


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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/11186145
(2) http://www.ncbi.nlm.nih.gov/pubmed/20833520
(3) http://www.ncbi.nlm.nih.gov/pubmed/19682881
(4) http://www.ncbi.nlm.nih.gov/pubmed/17433649
(5) http://www.ncbi.nlm.nih.gov/pubmed/12164265
(6) http://www.ncbi.nlm.nih.gov/pubmed/19067380