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Sunday, 10 November 2013

Phytochemicals: 7 Health Benefits of Dillapiole

Dillapiole a phytochemical monophenols, essential oil commonly extracted from dill weed, but can also be found in variety of other plants.

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Health Benefits
1. Anti-inflammatory activity
In the evaluation of essential oil (dillapiole) of Piper aduncum L. (Piperaceae) and it anti-inflammatory activity found that dillapiole and di-hydrodillapiole have moderate anti-phlogistic properties, indicating that they can be used as prototypes for newer anti-inflammatory compounds, according to "The anti-inflammatory activity of dillapiole and some semisynthetic analogues" by Parise-Filho R, Pastrello M, Pereira Camerlingo CE, Silva GJ, Agostinho LA, de Souza T, Motter Magri FM, Ribeiro RR, Brandt CA, Polli MC.(1)

2 . Liver, 3. Colon, 4. Breast cancer cell line
In the evaluation of essential oil and their anti-cancer effects found that simultaneous hydrodistillation-solvent (n-pentane) extraction sample showed the most potent activity against the3 human cancers (with IC50) values of 1.67, 1.34, and 3.38 microg/ml against the liver, colon, and breast cancer cell lines, according to the study of "Effect of the method of preparation on the composition and cytotoxic activity of the essential oil of Pituranthos tortuosus" by Abdallah HM, Ezzat SM.(2)

5. Antibacterial activities
In the observation of root oil dominated by dillapiole (47.4%) and myristicin (19.2%) from Ridolfia segetum, a traditional medicinal plant widely distributed in Tunisia and its antibacterial and antioxidant effects found that he minimum inhibitory concentrations of the essential oil varied between 1.25 and 5 mg mL(-1) and the minimum bactericidal concentrations were superior to 5 mg mL(-1) of oil for most strains, according to "Chemical composition and in vitro evaluation of antioxidant and antibacterial activities of the root oil of Ridolfia segetum (L.) Moris from Tunisia" by Jabrane A, Ben Jannet H, Mastouri M, Mighri Z, Casanova J.(3)

6. Anti houseflies Muscadomestica
In the analyzing the efficacy of seven natural compounds compared with piperonyl butoxide (PBO) in synergising pyrethrum and their effect in house fliers found that Dillapiole oil and parsley seed oil showed the greatest potential as pyrethrum synergists, according to "Investigating the potential of selected natural compounds to increase the potency of pyrethrum against houseflies Muscadomestica (Diptera: Muscidae)" by Joffe T, Gunning RV, Allen GR, Kristensen M, Alptekin S, Field LM, Moores GD.(4)

7. Psychotropic Phenylisopropylamines
In the investigation of psychotropic phenylisopropylamines (amphetamines) possess ring-substitution patterns identical to those of natural essential oils found that beta-phenethylamines may participate in central nervous system metabolism through ring closure with the formation of an indole intermediate and several phenolic amines are known to act as neurotransmitters. Methylated and methoxylated analogues might function directly, according to "Psychotropic Phenylisopropylamines derived from Apiole and Dillapiole" by Alexander T. Shulgin Nature 215, 1494-95 (1967)( 5)

8. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22014265
(2) http://www.ncbi.nlm.nih.gov/pubmed/21630588
(3) http://www.ncbi.nlm.nih.gov/pubmed/20397101
(4) http://www.ncbi.nlm.nih.gov/pubmed/21770012
(5) http://www.erowid.org/archive/rhodium/chemistry/dmmda.shulgin.html