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Monday, 25 November 2013

Chronic Low back pain - The Signs and Symptoms

 Low back pain is a Musculoskeletal disorders (MSDs, affecting over 80% of the population in US alone some points in their life. Chronic LBP (pain has persisted for longer than 3 months(1) prevalence in older adults was significantly higher than the 21-to-44-year age group (12.3% vs. 6.5%, p < .001). Older adults were more disabled, had longer symptom duration, and were less depressed(2)..Many older adults remain quite functional despite CLBP, and because age-related comorbidities often exist independently of pain (e.g., medical illnesses, sleep disturbance, mobility difficulty), the unique impact of CLBP is unknown. We conducted this research to identify the multidimensional factors that distinguish independent community dwelling older adults with CLBP from those that are pain-free(3).

I. Signs and symptoms
1. Pain has persisted for longer than 3 months as mentioned above
2. Degenerative disc disease
In a study to assess SPARC-null mice as an animal model of chronic low back and/or radicular pain caused by degenerative disc disease, showed that
a. Movement-evoked discomfort
b. Hypersensitivity to cold stimuli(4)
3. Morning stiffness, as a result of inflammation due to aging causes of degenerated discs(5)
4. Sleep interruptions due to pain
5. Higher compressive axial and tensile radial strains(6)
6. Depression, anxiety disorders and adjustment disorders
In the study of 127 patients suffering from chronic back pain in multimodal inpatient pain therapy who were assessed by a psychologist, showed that there was a high prevalence of depression, anxiety disorders and adjustment disorders in patients with chronic back pain(7).
7. Pain interfered with daily living, depressivity, and quality of life(8).
8. Diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain
due to chronic osteoarthritis (OA) pain and chronic low back pain (LBP)(9).
9. Metabolic syndrome
The prevalence of metabolic syndrome among chronic lower back pain patients was 36.2% (30.2% male, 38.6% female), according to the study by Department of Rehabilitation Medicine, Seoul Medical Center(9a)

10. Etc.
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Sources

Sources
(a) http://en.wikipedia.org/wiki/Low_back_pain 
(1) https://www.mja.com.au/journal/2004/180/2/management-chronic-low-back-pain
(2) http://jah.sagepub.com/content/22/8/1213.refs
(3) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2065872/
(4) http://www.ncbi.nlm.nih.gov/pubmed/20714283
(5) http://www.ncbi.nlm.nih.gov/pubmed/17543240
(6) http://www.ncbi.nlm.nih.gov/pubmed/21337394
(7) http://www.ncbi.nlm.nih.gov/pubmed/23149491
(8) http://www.ncbi.nlm.nih.gov/pubmed/11845338
(9) http://www.ncbi.nlm.nih.gov/pubmed/22716295