Friday 1 November 2013

Chinese Herbs – Wu Bei Zi (Gallae Rhois Chinensis)

Wu Bei Zi is also known as Chinese Gall. The aour, tart and cold herb has been used in TCM to treat chronic cough, chronic diarrhea with or without infection, spermatorrhea, night sweating, bleeding not during menses, etc., as it restrains Lungs, moves Fire downwards, strengthens the Intestines andthe Essence, prevents sweating, stops bleeding, etc. by enhancing the functions of lung, large intestine and kidney channels.

Ingredients
1. Cucupine
2. Indole-3-acetic acid
3. Octopinic aciad
4. Lysopine
5. Nopalinic acid
6. N5 -(1-carboxyethyl) ornithine, g;ucosyl (1–>4)-3-deoxy-2-heptulosaric acid
7. Rhamnosyl (1–>5) -3-deoxy-2-heptulosaric acid
8. Etc.

Health Benefits
1. TPA- and cigarette smoke condensate
Extact of Rhus chinensis Mill, at a concentration of 50 micrograms/ml it could significantly prevent the DNA damaging effects induced by TPA (100 ng/ml) or cigarette smoke condensate (400 micrograms/ml). At concentrations of 5 micrograms/ml and 80 micrograms/ml, it could effectively scavenge the O2-. produced by VB2 + hv and cigarette smoke condensate, respectively. The lipid peroxidation of red cell membrane induced by H2O2 was decreased significantly by tannic acid at a concentration of 5 micrograms/ml., according to the study of Dr. Fu N. at the Institute of Oncology, Beijing(1).
2. Breast cancer
In the study to determine the effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound isolated from Rhus chinensis Mill in treating breast cancer, showed that through the Beadstudio v3 micro assay program to compare the identified genes expressed in PGG-treated MDA-MB-231 cells with untreated control, several unique genes that are closely associated with pyruvate metabolism, glycolysis/gluconeogenesis and tyrosine metabolism, including PC, ACSS2, ACACA, ACYP2, ALDH3B1, FBP1, PRMT2 and COMT. Consistent with microarray data, real-time RT-PCR confirmed the significant down-regulation of these genes at mRNA level in PGG-treated MDA-MB-231 cells. Our findings suggest the potential of PGG as anticancer agent for breast cancer cells by targeting cancer metabolism genes(2).
3. Etc.

Side Effects
1. Do not use in case of diarrhea due to damp-heat
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/1839253
(2) http://www.ncbi.nlm.nih.gov/pubmed/21614488

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