Saturday 2 November 2013

Chinese Herbs – Shi Liu Pi (Pericarpium Punicae Granati)

Shi Liu Pi is also known as Pomegranate Peel. The sour, tart, warm and slightly toxic herb has been used in TCM to chronic diarrhea, chronic dysentery, with bleeding, get rid of parasite, yeast infection, etc., as it stops incontinence of stools and anal ptosis, eliminates parasites, etc. by enhancing the functions of large intestine channels.

Ingredients
1. Pelltierine
2. Isoquercetrin
3. Inulin
4. Mannitol
5. Tanin
6. Mallic aid
7. Calcium oxalate
8. Etc.

Health Benefits
1. Antimicrobial activity
In the study to evaluate twenty traditional Chinese medicines (TCM) for their antimicrobial activity against four common oral bacteria, found that thirteen TCMs demonstrated antimicrobial activity against Porphyromonas gingivalis, including Pericarpium granati(1).
2. Antioxidant activities
In the study to evaluate the demonstration of intake of polyphenols in health-promoting and disease-preventive effects, showed that the antioxidant capacity measured with the oxygen radical absorbance capacity (ORAC) assay was increased with a maximum effect of 32% after 0.5 h, whereas the generation of reactive oxygen species (ROS) was not affected. The inflammation marker interleukin-6 (IL-6) was not significantly affected after 4 h after the consumption of the extract(2)
3. Anti-inflammatory effects
In the study to investigate the anti-inflammatory properties of a pomegranate fruit husk (PomH) polyphenolic extract, rich in punicalagin, using Caco-2 cells, an in vitro model of human intestinal epithelium, indicated that pomegranate husk could be an interesting natural source contributing to prevent intestinal chronic inflammation(3).
4. Antidiabetic and antihyperlipidemic effects
In the study to investigate the antidiabetic and antihyperlipidemic effects of ethanolic extract of leaves of P. granatum in alloxan-induced diabetic rats (Groups A and B received normal saline [(10 ml/kg/day/per oral (p.o.)]; group C received ethanolic extract of leaves of P. granatum (500 mg/kg/p.o.); and group D received glibenclamide (0.5 mg/kg/day/p.o.)), researchers showed that Group B showed a significant (P<0.01) increase in blood glucose as compared to group A. Groups C and D showed significant decrease (P<0.01) in blood glucose level in comparison to group B. The test drug showed a significant (P<0.01) increase in glycogen content in the liver, cardiac, and skeletal muscle; it significantly (P<0.01) reduced intestinal glucose absorption. Groups C and D showed significant (P<0.01) decrease in serum TC, TG, LDL, and AI as compared to Group B, which showed a significant (P<0.01) increase. Groups C and D showed significant (P<0.01) increase in serum HDL as compared to Group B, which showed a significant (P<0.01) decrease in all values(4).
5. Learning and memory performances 
In the study to investigate of Pomegranate (Punica granatum L.) flower in improving learning and memory performances impaired by diabetes mellitus in rats, showed that Supplementation of PGF led to improvements in learning and memory performances of diabetic rats.While lipid peroxidation (LPO) was increased (P<0.001), glutathione (GSH) content was decreased (P<0.001) in hippocampal tissue of STZ-induced diabetic rats when compared with control values. Supplementation of PGF restored the levels of LPO and GSH towards their control values. Daily PGF supplementation to diabetic rats reduced the increase in glial-fibrilar acidic protein (GFAP) contents induced by diabetes in the hippocampus, which was significant in STZ + PGF III in comparison to STZ group (p<0.05)(5).
6. Etc.

Side Effects
1. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
2. The herb may cause cause nausea, vomiting, diarrhea, headache, dizziness, tinnitus, etc.
3. Prolonged period of usage can cause liver damage and diseases
4. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20418062
(2) http://www.ncbi.nlm.nih.gov/pubmed/17090147
(3) http://www.ncbi.nlm.nih.gov/pubmed/22733173
(4) http://www.ncbi.nlm.nih.gov/pubmed/22529479
(5) http://www.ncbi.nlm.nih.gov/pubmed/22173022

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