Wu Yao is also known as Spicebush Root. The
acrid and warm herb has been used in TCM as increased metabolism,
antibiotic, anti-viral agent andto harmonize peristalsis of digestive
tract, release intestinal gas, etc., as it moves Qi, warms the Kidneys.
calms pain, etc. by enhancing the functions of lung, spleen, kidney and
bladder.channels.
Ingredients
1. Hydrocarbon
2. Ester
3. Acidic sesquiterpenoid
4. Linderol (borneol)
5. α-terpinene
6. Isolinderoxide
7. Linderene
8. Isogermafurene
9. Linderane
10. Linderalactone
11. Isolinderalactone
12. Neolinderalactone
13. Etc.
Health Benefits
1. Arthritis
In the study to investigate the therapeutic potential of norisoboldine, the major isoquinoline alkaloid present in Radix Linderae, in collagen II -induced arthritis (CIA) of mice as well as the possible mechanisms, showed that norisoboldine might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses(1).
2. Reduced pro inflammatory effects
In the study to explore the effects of norisoboldine on the production of pro-inflammatory cytokines from macrophages stimulated by lipopolysaccharide, researchers at the China Pharmaceutical University, showed that the preventive effects of norisoboldine on the release of pro-inflammatory cytokines were correlated with the inhibitory action on the phosphorylations of mitogen-activated protein (MAP) kinases including p38, extracellular signal-regulated kinase (ERK) and c-jun NH(2)-terminal kinase (JNK), but not on the activation and translocation of nuclear factor-κB (NF-κB)(2).
3. Antioxidant activity
In the study to evaluate the antioxidant capacity and quality of traditional Chinese medicines using TLC-bioautography. indicated that Radix Linderae cultivated in Tiantai (Zhejiang province), Cortex Magnoliae Officinalis cultivated in Liangshan (Sichuan province), and Fructus Perillae acquired in Shanghai have the highest scavenging properties towards DPPH in their respective TLC-autographic assays. Norisoboldine, magnolol and honokiol, luteolin, apigenin and an unknown compound “U” proved to be the major antioxidant components in the corresponding crude drugs as they contribute the dominating peak areas to the total ones(3).
4. Diabetic nephropathy
In the study to examine a possible preventive effect of Linderae radix (LR), the root of Lindera strychnifolia, on the progression of diabetic nephropathy. Water extract of Linderae radix (LR extract) was orally administered to the C57BL/KsJ-db/db (db/db) mice, a model of genetic diabetes, at a dose of 730 mg/kg/day for 12 week, researchers at the Gifu University School of Medicine, found that the LR extract treatment did not affect glucose metabolism and systolic pressure. However, it resulted in a better renal function as evaluated by creatinine clearance (Ccr) and serum creatinine than the control; Ccr and serum creatinine were progressively worsened in controls (0.13+/-0.01 (l/day) and 0.69+/-0.04 (mg/dl), respectively) whereas unchanged in the treated group (0.24+/-0.03 (l/day), p<0.05 and 0.53+/-0.04 (mg/dl), p<0.05, respectively)(4).
5. Etc.
Side Effects
1. Do not use in case of Yin or Qi deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20363113
(2) http://www.ncbi.nlm.nih.gov/pubmed/20352482
(3) http://www.ncbi.nlm.nih.gov/pubmed/17184113
(4) http://www.ncbi.nlm.nih.gov/pubmed/15925389
Ingredients
1. Hydrocarbon
2. Ester
3. Acidic sesquiterpenoid
4. Linderol (borneol)
5. α-terpinene
6. Isolinderoxide
7. Linderene
8. Isogermafurene
9. Linderane
10. Linderalactone
11. Isolinderalactone
12. Neolinderalactone
13. Etc.
Health Benefits
1. Arthritis
In the study to investigate the therapeutic potential of norisoboldine, the major isoquinoline alkaloid present in Radix Linderae, in collagen II -induced arthritis (CIA) of mice as well as the possible mechanisms, showed that norisoboldine might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses(1).
2. Reduced pro inflammatory effects
In the study to explore the effects of norisoboldine on the production of pro-inflammatory cytokines from macrophages stimulated by lipopolysaccharide, researchers at the China Pharmaceutical University, showed that the preventive effects of norisoboldine on the release of pro-inflammatory cytokines were correlated with the inhibitory action on the phosphorylations of mitogen-activated protein (MAP) kinases including p38, extracellular signal-regulated kinase (ERK) and c-jun NH(2)-terminal kinase (JNK), but not on the activation and translocation of nuclear factor-κB (NF-κB)(2).
3. Antioxidant activity
In the study to evaluate the antioxidant capacity and quality of traditional Chinese medicines using TLC-bioautography. indicated that Radix Linderae cultivated in Tiantai (Zhejiang province), Cortex Magnoliae Officinalis cultivated in Liangshan (Sichuan province), and Fructus Perillae acquired in Shanghai have the highest scavenging properties towards DPPH in their respective TLC-autographic assays. Norisoboldine, magnolol and honokiol, luteolin, apigenin and an unknown compound “U” proved to be the major antioxidant components in the corresponding crude drugs as they contribute the dominating peak areas to the total ones(3).
4. Diabetic nephropathy
In the study to examine a possible preventive effect of Linderae radix (LR), the root of Lindera strychnifolia, on the progression of diabetic nephropathy. Water extract of Linderae radix (LR extract) was orally administered to the C57BL/KsJ-db/db (db/db) mice, a model of genetic diabetes, at a dose of 730 mg/kg/day for 12 week, researchers at the Gifu University School of Medicine, found that the LR extract treatment did not affect glucose metabolism and systolic pressure. However, it resulted in a better renal function as evaluated by creatinine clearance (Ccr) and serum creatinine than the control; Ccr and serum creatinine were progressively worsened in controls (0.13+/-0.01 (l/day) and 0.69+/-0.04 (mg/dl), respectively) whereas unchanged in the treated group (0.24+/-0.03 (l/day), p<0.05 and 0.53+/-0.04 (mg/dl), p<0.05, respectively)(4).
5. Etc.
Side Effects
1. Do not use in case of Yin or Qi deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
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Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20363113
(2) http://www.ncbi.nlm.nih.gov/pubmed/20352482
(3) http://www.ncbi.nlm.nih.gov/pubmed/17184113
(4) http://www.ncbi.nlm.nih.gov/pubmed/15925389
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