Huang Jing is also known as Solomon’s Seal. The
sweet and neutral herb has been used in TCM as anti-fungal, antibiotic,
anti lipid oxidative and anti-stress agent and to lower blood sugar,
blood pressure, improve cardiac function and to treat weak digestion,
lack of energy, tired, dry mouth, dry cough, etc., as it moistens the
Lungs, nourishes Lung-Yin, tonifies the Spleen, benefits the Qi, etc.,
by enhancing the functions of spleen, lung and kidney channels
Ingredients
1. 26-O-β-D-glucopyranosyl-22-O-methyl-25
2. 26-diol3-O-β-lycotetraoside (sibiricoside-A)
2. 26-diol3-O-β-lycotetraoside (sibiricoside-A)
3. 26-O-β-D-glucopyranosyl-22-O-methyl-25
4. 26-triol 3-O-β-lycotetraoside (sibiricoside B)
5. Neoprazerigenin A 3-O-β-lycotetraoside6. Mannose acid
7. Galacturonic acid
8. Etc.
Health Benefits
1. Hypoglycemic activity
In the investigation of the hypoglycemic effect of different dose of Polygonati Rhizoma, i.e., “Ousei”, in both normal and streptozotocin-induced diabetic mice, showed that the methanol extract of Polygonati Rhizoma (OM) (800 mg/kg) reduced the blood glucose of normal mice from 202 +/- 7 to 144 +/- 13 mg/100 ml 4 h after intraperitoneal administration (p < 0.01), and also lowered significantly the blood glucose of streptozotocin-induced diabetic mice from 589 +/- 34 to 396 +/- 15 mg/100 ml under similar conditions (p < 0.001). However, the hypoglycemic effects were not accompanied by any alteration in the serum insulin in these mice. OM also suppressed epinephrine-induced hyperglycemia in mice, according to “Hypoglycemic activity of polygonati rhizoma in normal and diabetic mice” by Kato A, Miura T.(1) 2. Diabetes prevention
In investigation of “diabetes is usually associated with inflammation. Inflammation contributes to the development of diabetes” from numbers of CTM with anti inflammatory and hypoglycaemic effects, found that TCM might exert hypoglycaemic effects that are partly mediated by the anti-inflammatory mechanisms. However, small amounts of TCM with potent anti-inflammatory action does not have any hypoglycaemic effect. This indirectly indicates that diabetes may be a low-grade inflammatory disease and potent regulation of inflammatory mediators may not be required. Studies of TCM add new evidences, which indicate that diabetes may be an inflammatory disease and slight or moderate inhibition of inflammation might be useful to prevent the development of diabetes, according to “Diabetes is an inflammatory disease: evidence from traditional Chinese medicines” by Xie W, Du L.(2)
3. Antihyperglycemic and antioxidative effects
In the investigation of the antidiabetic effects of a new herbal formula (NHF) consisting of Polygonati Rhizoma, Rehmanniae Radix, Salviae Miltiorrhizae Radix, Puerariae Radix, Schizandrae Fructus, and Glycyrrhizae Radix. Streptozotocin-induced diabetic rats were orally administered NHF (300 mg/kg of body weight/day) for 4 weeks, the result showed that NHF treatment significantly increased plasma insulin levels and the number and size of insulin-immunoreactive cells in the pancreas of diabetic rats. Administration of NHF significantly lowered the levels of TBARS and increased the activities of SOD, CAT, and GSH-Px in the liver of diabetic rats. In addition, treatment with NHF increased the mRNA levels of GLUT4 in soleus muscle. Therefore NHF may be an effective preventive and therapeutic agent for diabetes mellitus, according to “Antihyperglycemic and antioxidative effects of new herbal formula in streptozotocin-induced diabetic rats” by Kim JO, Kim KS, Lee GD, Kwon JH.(3)
4. Cancer prevention
In the investigation of the effect of extracts of some Chinese medical herbs on DNA nicking induced by alternariol.the result of results indicate that substances from FL and RP may be used as DNA protectors. It is possible that they play an important role in preventing cancer, according to “The inhibitory effect of extracts from Fructus lycii and Rhizoma polygonati on in vitro DNA breakage by alternariol” by Xu DS, Kong TQ, Ma JQ.(4)
5. Anti aging
In a report of the studies on 386 traditional effective anti-aging medications, the effects of which on cell generation, survival time, immunomodulation, improvement of visceral and metabolic functions, and anti-infection, and their trace element contents, showed that traditional anti-aging materia medica in China are now well under way and some effective drugs and compound prescriptions have been explored, such as Ginseng, Radix Astragali seu Hedysari, Radix Angelicae Sinensis, Herba Epimedii, Cordyceps, Ganoderma Lucidum seu Japonicum, Radix Polygoni Multiflori, Radix Acanthopanacis Senticosi, Rhizoma Polygonati, Fructus Lycii, and Poria, according to “Recent advances in studies on traditional Chinese anti-aging materia medica” by Chen K, Li C.(5)
6. Etc.
1. Hypoglycemic activity
In the investigation of the hypoglycemic effect of different dose of Polygonati Rhizoma, i.e., “Ousei”, in both normal and streptozotocin-induced diabetic mice, showed that the methanol extract of Polygonati Rhizoma (OM) (800 mg/kg) reduced the blood glucose of normal mice from 202 +/- 7 to 144 +/- 13 mg/100 ml 4 h after intraperitoneal administration (p < 0.01), and also lowered significantly the blood glucose of streptozotocin-induced diabetic mice from 589 +/- 34 to 396 +/- 15 mg/100 ml under similar conditions (p < 0.001). However, the hypoglycemic effects were not accompanied by any alteration in the serum insulin in these mice. OM also suppressed epinephrine-induced hyperglycemia in mice, according to “Hypoglycemic activity of polygonati rhizoma in normal and diabetic mice” by Kato A, Miura T.(1) 2. Diabetes prevention
In investigation of “diabetes is usually associated with inflammation. Inflammation contributes to the development of diabetes” from numbers of CTM with anti inflammatory and hypoglycaemic effects, found that TCM might exert hypoglycaemic effects that are partly mediated by the anti-inflammatory mechanisms. However, small amounts of TCM with potent anti-inflammatory action does not have any hypoglycaemic effect. This indirectly indicates that diabetes may be a low-grade inflammatory disease and potent regulation of inflammatory mediators may not be required. Studies of TCM add new evidences, which indicate that diabetes may be an inflammatory disease and slight or moderate inhibition of inflammation might be useful to prevent the development of diabetes, according to “Diabetes is an inflammatory disease: evidence from traditional Chinese medicines” by Xie W, Du L.(2)
3. Antihyperglycemic and antioxidative effects
In the investigation of the antidiabetic effects of a new herbal formula (NHF) consisting of Polygonati Rhizoma, Rehmanniae Radix, Salviae Miltiorrhizae Radix, Puerariae Radix, Schizandrae Fructus, and Glycyrrhizae Radix. Streptozotocin-induced diabetic rats were orally administered NHF (300 mg/kg of body weight/day) for 4 weeks, the result showed that NHF treatment significantly increased plasma insulin levels and the number and size of insulin-immunoreactive cells in the pancreas of diabetic rats. Administration of NHF significantly lowered the levels of TBARS and increased the activities of SOD, CAT, and GSH-Px in the liver of diabetic rats. In addition, treatment with NHF increased the mRNA levels of GLUT4 in soleus muscle. Therefore NHF may be an effective preventive and therapeutic agent for diabetes mellitus, according to “Antihyperglycemic and antioxidative effects of new herbal formula in streptozotocin-induced diabetic rats” by Kim JO, Kim KS, Lee GD, Kwon JH.(3)
4. Cancer prevention
In the investigation of the effect of extracts of some Chinese medical herbs on DNA nicking induced by alternariol.the result of results indicate that substances from FL and RP may be used as DNA protectors. It is possible that they play an important role in preventing cancer, according to “The inhibitory effect of extracts from Fructus lycii and Rhizoma polygonati on in vitro DNA breakage by alternariol” by Xu DS, Kong TQ, Ma JQ.(4)
5. Anti aging
In a report of the studies on 386 traditional effective anti-aging medications, the effects of which on cell generation, survival time, immunomodulation, improvement of visceral and metabolic functions, and anti-infection, and their trace element contents, showed that traditional anti-aging materia medica in China are now well under way and some effective drugs and compound prescriptions have been explored, such as Ginseng, Radix Astragali seu Hedysari, Radix Angelicae Sinensis, Herba Epimedii, Cordyceps, Ganoderma Lucidum seu Japonicum, Radix Polygoni Multiflori, Radix Acanthopanacis Senticosi, Rhizoma Polygonati, Fructus Lycii, and Poria, according to “Recent advances in studies on traditional Chinese anti-aging materia medica” by Chen K, Li C.(5)
6. Etc.
Side effects
1. Do not use the herb in case of spleen deficiency2. Do not use the herb in case of cough and abundance of phlegm
3. Do not use Huang Jing in newborn, children or if you are pregnant or breast feeding with out approval first with the related field specialist
4. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/8312868
(2) http://www.ncbi.nlm.nih.gov/pubmed/21205111
(3) http://www.ncbi.nlm.nih.gov/pubmed/19735171
(4) http://www.ncbi.nlm.nih.gov/pubmed/8721630
(5) http://www.ncbi.nlm.nih.gov/pubmed/8246603
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