Huai Niu Xi, Huai Niu Qi, or Huai Qi is also known
as achyranthes root. The bitter, sour and neutral herb has been used in
TCM as Anti-hypertensive, Anti-inflammatory and analgesic, Anti-aging
and Anti spasm agent and to enhance immune system, treat irregular
menses, postpartum pain in abdomen, etc., as it moves Blood, eliminates
Blood accumulation, tonifies Liver and Kidneys, strengthens the sinews
and bones, etc., by enhancing the functions of liver and kidney
channels.
Ingredients
1. Achyranthes bidentata polysaccharide
2. Ecdysterone
3. Saponins4 Mucilage
5. Potassium salt
6. Nickel
7. Iron
8. Manganese
9. Chronium
10. Copper
11. Etc.
Health Benefits
1. Osteonecrosis of the femoral head (ONFH)
In the investigation of the effect of Huogu II Formula (II) with medicinal guide Radix Achyranthis Bidentatae (Ach) on bone marrow stem cells (BMSCs) homing to necrosis area after osteonecrosis of the femoral head (ONFH) frozen by liquid nitrogen in rabbit as well as exploring the mechanism of prevention and treatment for ONFH, indicated that to a certain extent, the medicinal guide Ach improves the preventive and therapeutic effects of Huogu II Formula on experimental ONFH model. The possible mechanism of this is related to its promoting effect on directional homing of BMSCs to the necrosis area, according to “Effect of Huogu II Formula (II) with medicinal guide radix Achyranthis Bidentatae on bone marrow stem cells directional homing to necrosis area after osteonecrosis of the femoral head in rabbit” by Kong XY, Wang RT, Tian N, Li L, Lin N, Chen WH.(1) 2. Generation of collagen I
In the investigation of the effect of a Chinese herbal prescription ((contains Radix Rehmanniae Praeparata, Radix Achyranthis Bidentatae, Radix Astragali, Radix Angelicae Sinensis, Concha Ostreae prepared by acetic acid)) on collagen I in rat’s femur under simulated weightlessness, showed that Generation of collagen I become weaken under simulated weightlessness, while the Chinese herbal prescription is effective to prevent the change, thus biochemistry environment of bone calcium deposition may be improved by this Chinese herbal prescription under simulated weightlessness, according to “[Effect of a Chinese herbal prescription on collagen I in rat's femur under simulated weightlessness].[Article in Chinese]” by Hu SM, Zhou P, Fu Q, Yang JJ, Gao XM.(2)
3. DNAprotective effect
In the study of the role of polyaccharide and flavone compounds of Flos lonicerae, Ganoderma lucidum etc. in protecting DNA with EB as a probe to determine the fluorescence integration intensity of DNA and EB mixture, showed that show that all the extracts from traditional Chinese herbs can interact with DNA, but the degree of interaction is different. The order is as follows: folium hippophae rhamnosides > rhizoma anemarrhenae > radix acanthopanacis senticosi > Ganoderma lucidum > radix achyranthis bidentatae > fructus lycii > Flos lonicerae > rhizoma atractylodis > Astragalus membranaceus > Flos chrysanthemi in the presence of polysaccharide compounds, while folium hippophae rhamnosides > Flos lonicerae > fructus lycii > rhizoma atractylodis > Astragalus membranaceus > rhizoma anemarrhenae > radix acanthopanacis senticosi > Ganoderma lucidum > radix achyranthis bidentatae (Flos chrysanthemi, with no signals) in the presence of flavone compounds, according to “[Study on the role of polysaccharide and flavone in Chinese herbs in protecting DNA with fluorescence probe].[Article in Chinese]” by Zhang HR, Wu XY.(3)
4. Antioxidants
In the investigation of using well established in vitro antioxidant assays employing 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and diphenyl-l-picrylhydrazyl (DPPH), showed that in addition to elevating endogenous antioxidant enzyme activity, Salvia miltiorrhiza and other CHM traditionally used for cardiovascular disorders (such as Rhizoma ligustici, Herba leonuri, Radix achyranthis bidentatae, and Camellia sinensis) contain potent antioxidant moieties in addition to their phenolic constituents, according to “Antioxidants in Chinese herbal medicines: a biochemical perspective” by Zhu YZ, Huang SH, Tan BK, Sun J, Whiteman M, Zhu YC.(4)
5. Memory and endurance
In the evaluation of P. O. decoction of Radix Achyranthis Bidentatae,
used continuously for seven days in mice, found that the drug could
effectively improve the acquisition of memory of mice, significantly
enhance the endurance of mice. The results indicated that the decoction
of Radix Achyranthis Bidentatae has the actions of enhancing memory and
endurance, according to “[Effect of radix Achyranthis bidentatae on
memory and endurance].1. Osteonecrosis of the femoral head (ONFH)
In the investigation of the effect of Huogu II Formula (II) with medicinal guide Radix Achyranthis Bidentatae (Ach) on bone marrow stem cells (BMSCs) homing to necrosis area after osteonecrosis of the femoral head (ONFH) frozen by liquid nitrogen in rabbit as well as exploring the mechanism of prevention and treatment for ONFH, indicated that to a certain extent, the medicinal guide Ach improves the preventive and therapeutic effects of Huogu II Formula on experimental ONFH model. The possible mechanism of this is related to its promoting effect on directional homing of BMSCs to the necrosis area, according to “Effect of Huogu II Formula (II) with medicinal guide radix Achyranthis Bidentatae on bone marrow stem cells directional homing to necrosis area after osteonecrosis of the femoral head in rabbit” by Kong XY, Wang RT, Tian N, Li L, Lin N, Chen WH.(1) 2. Generation of collagen I
In the investigation of the effect of a Chinese herbal prescription ((contains Radix Rehmanniae Praeparata, Radix Achyranthis Bidentatae, Radix Astragali, Radix Angelicae Sinensis, Concha Ostreae prepared by acetic acid)) on collagen I in rat’s femur under simulated weightlessness, showed that Generation of collagen I become weaken under simulated weightlessness, while the Chinese herbal prescription is effective to prevent the change, thus biochemistry environment of bone calcium deposition may be improved by this Chinese herbal prescription under simulated weightlessness, according to “[Effect of a Chinese herbal prescription on collagen I in rat's femur under simulated weightlessness].[Article in Chinese]” by Hu SM, Zhou P, Fu Q, Yang JJ, Gao XM.(2)
3. DNAprotective effect
In the study of the role of polyaccharide and flavone compounds of Flos lonicerae, Ganoderma lucidum etc. in protecting DNA with EB as a probe to determine the fluorescence integration intensity of DNA and EB mixture, showed that show that all the extracts from traditional Chinese herbs can interact with DNA, but the degree of interaction is different. The order is as follows: folium hippophae rhamnosides > rhizoma anemarrhenae > radix acanthopanacis senticosi > Ganoderma lucidum > radix achyranthis bidentatae > fructus lycii > Flos lonicerae > rhizoma atractylodis > Astragalus membranaceus > Flos chrysanthemi in the presence of polysaccharide compounds, while folium hippophae rhamnosides > Flos lonicerae > fructus lycii > rhizoma atractylodis > Astragalus membranaceus > rhizoma anemarrhenae > radix acanthopanacis senticosi > Ganoderma lucidum > radix achyranthis bidentatae (Flos chrysanthemi, with no signals) in the presence of flavone compounds, according to “[Study on the role of polysaccharide and flavone in Chinese herbs in protecting DNA with fluorescence probe].[Article in Chinese]” by Zhang HR, Wu XY.(3)
4. Antioxidants
In the investigation of using well established in vitro antioxidant assays employing 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and diphenyl-l-picrylhydrazyl (DPPH), showed that in addition to elevating endogenous antioxidant enzyme activity, Salvia miltiorrhiza and other CHM traditionally used for cardiovascular disorders (such as Rhizoma ligustici, Herba leonuri, Radix achyranthis bidentatae, and Camellia sinensis) contain potent antioxidant moieties in addition to their phenolic constituents, according to “Antioxidants in Chinese herbal medicines: a biochemical perspective” by Zhu YZ, Huang SH, Tan BK, Sun J, Whiteman M, Zhu YC.(4)
5. Memory and endurance
[Article in Chinese]” by Ma A, Guo H.(5)
6. Anti aging
In the investigation of oral administration of the decoction of Radix Achyranthes Bidentatae for 30 days, showed that the SOD vigour in the senile model mice had been raised and the plasma LPO reduced, according to “[Study of old-age-resistant function of Radix Achyranthes Bidentatae].[Article in Chinese]” by Ma A, Guo H.(6)
7. Etc.
In the investigation of oral administration of the decoction of Radix Achyranthes Bidentatae for 30 days, showed that the SOD vigour in the senile model mice had been raised and the plasma LPO reduced, according to “[Study of old-age-resistant function of Radix Achyranthes Bidentatae].[Article in Chinese]” by Ma A, Guo H.(6)
7. Etc.
Side effects
1. Do not use the Huai Niu Xi in newborn, children or if you are
pregnant or breast feedign with out approval first with the related
field specialist2. Spleen deficiency cause of diarrhea
3. Qi deficiency cause of excessive menstruation or spermatorrhea
4. Etc.
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22241502
(2) http://www.ncbi.nlm.nih.gov/pubmed/20345035
(3) http://www.ncbi.nlm.nih.gov/pubmed/17514973
(4) http://www.ncbi.nlm.nih.gov/pubmed/15282631
(5) http://www.ncbi.nlm.nih.gov/pubmed/12569679
(6) http://www.ncbi.nlm.nih.gov/pubmed/12569859
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